WebMar 15, 2024 · A total of 47 received weekly carboplatin, of whom 83% received at least 11 of 12 planned doses, and 29 received every 3-week carboplatin, of whom 90% received all 4 planned doses. pCR rates were similar, 53% with weekly and 55% with every 3-week carboplatin dosing. WebThe internationally recommended maximum dose of carboplatin for AUC 5 is 750mg. The national dose bands do not contain this dose so the cap has been set at 790mg in ARIA. …
CARBOplatin - Cancer Care Ontario
WebHigh-Dose Chemotherapy Regimens Preferred Regimens Carboplatin + Etoposide 11 Carboplatin 700mg/m 2 IV Etoposide 750mg/m 2 IV. Administer 5, 4 and 3 days before peripheral blood stem cell infusion ... WebCarboplatin dose is based on the Calvert formula: Dosage = Target AUC x (GFR* + 25) *Where the GFR is provided by the eCrCl. Carboplatin and target AUC The carboplatin dosage value takes account of the target area concentration versus time curve and estimated GFR. ticketmaster code promo
5PSQ-153 Carboplatin AUC dosing in paediatric patients: influence …
WebOct 21, 2024 · AUC is influenced by drug dose and schedule, and patient-specific factors such as age, gender, height, weight, concomitant medications, inherited variations in drug metabolizing enzymes, drug transporters, and/or drug targets, and drug clearance (which depends on renal and hepatic function). WebDose of carboplatin 300 mg/m2 300 mg/m2 Dose of cyclophosphamide 600 mg/m2 600 mg/m2 Residual tumor <2 cm (number of patients) 39% (174/447) 14% (49/342) Clinical … WebThe use of the Calvert formula to calculate carboplatin doses allows clinicians to achieve the appropriate carboplatin area under the concentration (AUC) curve. … the lion king 2 ambush