Chromosome substitution strains

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August undefined, 2024

WebMay 23, 2024 · chromosome substitution The replacement of one or more chromosomes by others (totally or partially homologous) from another source (either a different strain of the same species or a related species that will permit hybridization) by a suitable crossing programme. A Dictionary of Zoology MICHAEL ALLABY WebRecombinant inbred (RI) and chromosome substitution (CS) strain panels Many common inherited human diseases — such as diabetes, cardiovascular disease, obesity, …

Chromosome Substitution Strain - an overview ScienceDirect Topics

WebJun 29, 2016 · Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently requires the identification of the respective phenotypic trait of interest and is simply based on a significant difference between a consomic and host strain. However, statistical significance as … WebJan 1, 2007 · By partitioning the genome into a panel of new inbred strains with single chromosome substitutions, one strain for each of the autosomes, the X and Y chromosome, and the mitochondria,... small toys for 8 year old boys

Karyotype showing trisomy 13, indicated by the extra copy of chromosome …

WebA chromosome substitution strain (CSS) is an inbred strain in which one chromosome has been substituted from a different inbred strain by repeated backcrossing. A complete CSS set has one strain representing each chromosome against a uniform background, thus allowing genome-wide scans to be carried out for quantitative trait loci (QTLs) … WebChromosome substitution strains (CSSs) are based on a different paradigm that deal with the signal-noise problem in a novel way ( 20 ). Each CSSs is an inbred strain that differs from the host strain by a single intact and homozygous chromosome on a defined and uniform genetic background. WebA chromosome substitution strain (CSS) or consomic strain is an inbred strain in which a single chromosome from a donor strain replaces the corresponding chromosome in … small toys for boys for easter baskets

Chromosome Substitution Strain - an overview - ScienceDirect

Special Mouse Strains Resource - The Jackson Laboratory

WebDec 16, 2008 · Chromosome substitution strains (CSSs) enable statistically powerful studies based on testing engineered inbred strains that have single, unique, and … WebJan 23, 2024 · Chromosome substitution strains, also known as consomic strains, provide a simple model for exploring genetic influences. They consist of a panel of strains where one chromosome of a host strain is replaced by a homologous chromosome of a donor strain ( Matin et al., 1999; Singer et al., 2004; Ishii et al., 2011 ). hii family health centerWebMay 23, 2024 · chromosome substitution The replacement of one or more chromosomes by others (totally or partially homologous) from another source (either a different strain … hii fair lakes office

"WebGenetic resistance to diet-induced obesity in chromosome substitution strains of mice.pdf. 2011-11-03 ... " - Chromosome substitution strains

Chromosome substitution strains

Genetic architecture of complex traits: Large phenotypic effects …

http://informatics.jax.org/nomen/strains.shtml WebFeb 1, 2006 · (3) Chromosome substitution strains (CSS) Chromosome substitution strains (CSS) are mice strains with one single chromosome replaced by the corresponding chromosome from a donor strain...

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WebChromosome Substitution Strains: A New Way to Study Genetically Complex Traits Article Full-text available Feb 2006 Annie E Hill-Baskin Eric S Lander Joseph H Nadeau Many biological traits and... WebChromosome substitution strains (CSSs) are a powerful complement to existing resources for studying multigenic traits. By partitioning the genome into a panel of …

WebJun 12, 2006 · An analysis of transcriptional variation in the liver using a panel of B.A chromosome substitution strains identified 4209 transcripts that are differentially expressed relative to the C57BL/6J background and 1010 transcripts that are differentially expressed between C57BL/6J and A/J strains. A subset of these strains (substituting … WebChromosome substitution strains QTL mapping can be accelerated using chromosome substitution strains (CSSs), which enable the first two steps above to be omitted. We …

WebNov 4, 2024 · Chromosome substitution strains C57BL/6J-Chr# A /J/NaJ (20, 23), hereafter referred to as CSS, for all chromosomes except Y and the mitochondrial genome, were purchased from the Jackson Laboratory (JAX, Bar Harbor, Maine) and imported to the University of Colorado Boulder. The JAX strain IDs for the CSS are continuous from … WebChromosome Substitution Strain Consomic. A consomic strain of animals is an inbred strain in which a whole chromosome – rather than one local... Genetic Monitoring of Laboratory Mice and Rats. Marjorie C. Strobel PhD, ... ... Congenic (and consomic) …

WebJan 1, 2007 · By partitioning the genome into a panel of new inbred strains with single chromosome substitutions, one strain for each of the autosomes, the X and Y chromosome, and the mitochondria,...

WebApr 16, 2004 · Chromosome substitution strains (CSSs) have been proposed as a simple and powerful way to identify quantitative trait loci (QTLs) affecting developmental, physiological, and behavioral processes. Here, we report the construction of a complete CSS panel for a vertebrate species. small toys for childrenWebDec 1, 2003 · Chromosome substitution strains (CSSs) are important in this resource portfolio because of their demonstrated use for gene discovery, genetic and epigenetic studies, functional characterizations ... hii family health center cvsWebSep 8, 2012 · Chromosome substitution strains (CSSs) are important in this resource portfolio because of their demonstrated use for gene discovery, genetic and epigenetic studies, functional characterizations,... hii family healthWebJAX® Mice substrains were used to generate panels of consomic (chromosome substitution) strains for use as gene mapping tools 21. The Complex Trait Consortium (www.complextrait.org) plans to use JAX® Mice substrains as progenitor strains for the generation of >500 recombinant inbred strains 22. small toys for claw machineWebA chromosome substitution strain (CSS) or consomic strain is an inbred strain in which a single chromosome from a donor strain replaces the corresponding chromosome in the host/parental strain on a defined and uniform genetic background. From:Handbook of Behavioral Neuroscience, 2016 Related terms: Phenotype Mutation Quantitative Trait Locus small toys for christmas crackersWebSep 8, 2012 · Chromosome substitution strains (CSSs) are important in this resource portfolio because of their demonstrated use for gene discovery, genetic and epigenetic … hii field service representativeWebJul 8, 2003 · A chromosome substitution strain (CSS) is an inbred strain in which one chromosome has been substi-tuted from a different inbred strain by repeated backcrossing. A complete CSS set has one strain representing each chromosome against a uniform background, thus allowing genome-wide scans to be carried out for … hii family health center hours